Papadakis M, Hadley G, Xilouri M, Hoyte LC, Nagel S, McMenamin MM, Tsaknakis G, Watt SM, Wright Drakesmith C, Chen R,  Wood MJA, Zhao Z, Kessler B, VekrellisK, Buchan AM. Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy. Nature Medicine 2013 DOI:doi:10.1038/nm.3097. View Article. The Economist. BBC News

Thézénas ML, Huang H, Njie M, Ramaprasad A, Nwakanma DC, Fischer R, Digleria K, Walther M, Conway DJ, Kessler BM, Casals-Pascual C. PfHPRT: a new biomarker candidate of acute Plasmodium falciparum infection. J Proteome Res. 2013 Jan 22. View Article



Frleta D, Ochoa CE, Kramer HB, Khan SA, Stacey AR, Borrow P, Kessler BM, Haynes BF, Bhardwaj N. HIV-1 infection-induced apoptotic microparticles inhibit human DCs via CD44. J Clin Invest. 2012 Nov 19. doi:pii: 64439.  10.1172/JCI64439. View Article

Chauhan D, Tian Z, Nicholson B, Kumar KG, Zhou B, Carrasco R, McDermott JL, Leach CA, Fulcinniti M, Kodrasov MP, Weinstock J, Kingsbury WD, Hideshima T, Shah PK, Minvielle S, Altun M, Kessler BM, Orlowski R, Richardson P, Munshi N, Anderson KC. A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. Cancer Cell. 2012 Sep 11;22(3):345-58. View Article

Huang H, Mackeen MM, Cook M, Oriero E, Locke E, Thezenas ML, Kessler BM, Nwakanma D, Casals-Pascual C. Proteomic identification of host and parasite biomarkers in saliva from patients with uncomplicated Plasmodium falciparum malaria. Malar J. 2012 May 28;11(1):178. [Epub ahead of print]. View Article

Konietzny R, Fischer R, Ternette N, Wright CA, Turney BW, Chakera A, Hughes D, Kessler BM, Pugh CW. 2012 Detection of BK virus in urine from renal transplant subjects by mass spectrometry. Clinical Proteomics 2012, 9:4 (26 April 2012), [Abstract] [Provisional PDF].

Fischer R, Trudgian DC, Wright C, Thomas G, Bradbury LA, Brown MA, Bowness P, Kessler BM. 2012. Discovery of candidate serum proteomic and metabolomic biomarkers in ankylosing spondylitis. Mol Cell Proteomics, 11 (2), Read more



Adam J, Hatipoglu E, O'Flaherty L, Ternette N, Sahgal N, Lockstone H, Baban D, Nye E, Stamp GW, Wolhuter K, Stevens M, Fischer R, Carmeliet P, Maxwell PH, Pugh CW, Frizzell N, Soga T, Kessler BM, El-Bahrawy M, Ratcliffe PJ, Pollard PJ. 2011. Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling. Cancer Cell, 20 (4). View Article

Bardella C, El-Bahrawy M, Frizzell N, Adam J, Ternette N, Hatipoglu E, Howarth K, O'Flaherty L, Roberts I, Turner G, Taylor J, Giaslakiotis K, Macaulay VM, Harris AL, Chandra A, Lehtonen HJ, Launonen V, Aaltonen LA, Pugh CW, Mihai R, Trudgian D, Kessler B, Baynes JW, Ratcliffe PJ, Tomlinson IP, Pollard PJ. 2011. Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status. J Pathol, 225 (1). View Article

Ranasinghe SRF, Kramer HB, Wright C, Kessler BM, di Gleria K, Zhang Y, Gillespie GM, Blais ME, Culshaw A, Pichulik T, Simmons A, Rowland-Jones SL, McMichael AJ, Dong T. The antiviral efficacy of HIV-specific CD8+ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate. PLoS Pathog 7(5): e1001341. doi:10.1371/journal.ppat.1001341. View Article

Wright CA, Howles S, Trudgian DC, Kessler BM, Reynard JM, Noble JG, Hamdy FC, Turney BW. Label-free quantitative proteomics reveals differentially regulated proteins influencing urolithiasis. Mol Cell Proteomics. 2011 Apr 7.  View article

El-Kasti MM, Wright C, Fye HK, Roseman F, Kessler BM, Becker CM. Urinary peptide profiling identifies a panel of putative biomarkers for diagnosing and staging endometriosis. Fertil Steril. 2011 Jan 19.  View Article




Sideso E, Papadakis M, Wright C, Handa A, Buchan A, Kessler B, Kennedy J. Assessing the Quality and Reproducibility of a Proteomic Platform for Clinical Stroke Biomarker Discovery. Trans. Stroke Res. DOI: 10.1007/s12975-010-0036-2 View Article

Kramer HB, Lavender KJ, Qin L, Stacey AR, Liu MKP, di Gleria K, Simmons A, Gasper-Smith N, Haynes BF, McMichael AJ, Borrow P, Kessler BM. Elevation of intact and proteolytic fragments of acute phase proteins constitutes the earliest systemic antiviral response in HIV-1 infection. PLoS Pathog. 2010 May 06: e1000893. View Article

Wright C, Sibani S, Trudgian D, Fischer R, Kessler B, Labaer J, Bowness P. Detection of multiple autoantibodies in patients with ankylosing spondylitis using nucleic acid programmable protein arrays. Mol Cell Proteomics. 2010 Feb 1. View Article





Monach PA, Hueber W, Kessler B, Tomooka BH, Benbarak M, Simmons BP, Wright J, Thornhill TS, Monestier M, Ploegh H, Robinson WH, Mathis D, Benoist C. A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis. Proc Natl Acad Sci USA. 2009 Sep 15;106(37):15867-72.. View Article

Wright C, Edelmann M, diGleria K, Kollnberger S, Kramer H, McGowan S, McHugh K, Taylor S, Kessler B, Bowness P. Ankylosing spondylitis monocytes show upregulation of proteins involved in inflammation and the ubiquitin proteasome pathway. Ann. Rheum. Dis. 2009 Oct;68(10):1626-32. View Article

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